As we officially enter Draft Week, the Steelers hold the 22nd overall pick in the first round. Below is a year-by-year look at each of the past selections at No. 22 since the first AFL-NFL Draft in 1967.
| YEAR | TEAM | NAME | POS. | COLLEGE |
| 2014 | Cleveland Browns | Johnny Manziel | QB | Texas A&M |
| 2013 | Atlanta Falcons | Desmond Trufant | CB | Washington |
| 2012 | Cleveland Browns | Brandon Weeden | QB | Oklahoma State |
| 2011 | Indianapolis Colts | Anthony Castonzo | T | Boston College |
| 2010 | Denver Broncos | Demaryius Thomas | WR | Georgia Tech |
| 2009 | Minnesota Vikings | Percy Harvin | WR | Florida |
| 2008 | Dallas Cowboys | Felix Jones | RB | Arkansas |
| 2007 | Cleveland Browns | Brady Quinn | QB | Notre Dame |
| 2006 | San Francisco 49ers | Manny Lawson | OLB | North Carolina State |
| 2005 | Baltimore Ravens | Mark Clayton | WR | Oklahoma |
| 2004 | Buffalo Bills | J.P. Losman | QB | Tulane |
| 2003 | Chicago Bears | Rex Grossman | QB | Florida |
| 2002 | New York Jets | Bryan Thomas | DE | Alabama-Birmingham |
| 2001 | New York Giants | Will Allen | CB | Syracuse |
| 2000 | Seattle Seahawks | Chris McIntosh | T | Wisconsin |
| 1999 | Seattle Seahawks | Lamar King | DE | Saginaw Valley State |
| 1998 | New England Patriots | Tebucky Jones | DB | Syracuse |
| 1997 | Dallas Cowboys | David LaFleur | TE | Louisiana State |
| 1996 | Tampa Bay Buccaneers | Marcus Jones | DT | North Carolina |
| 1995 | Carolina Panthers | Tyrone Poole | CB | Fort Valley State |
| 1994 | Los Angeles Raiders | Rob Fredrickson | OLB | Michigan State |
| 1993 | San Diego Chargers | Darrien Gordon | CB | Stanford |
| 1992 | Chicago Bears | Alonzo Spellman | DE | Ohio State |
| 1991 | Chicago Bears | Stan Thomas | T | Texas |
| 1990 | Philadelphia Eagles | Ben Smith | DB | Georgia |
| 1989 | Indianapolis Colts | Andre Rison | WR | Michigan State |
| 1988 | Houston Oilers | Lorenzo White | RB | Michigan State |
| 1987 | San Francisco 49ers | Harris Barton | G | North Carolina |
| 1986 | New York Jets | Mike Haight | G | Iowa |
| 1985 | Chicago Bears | William Perry | DT | Clemson |
| 1984 | Seattle Seahawks | Terry Taylor | DB | Southern Illinois |
| 1983 | San Diego Chargers | Gill Byrd | DB | San Jose State |
| 1982 | Green Bay Packers | Ron Hallstrom | T | Iowa |
| 1981 | Cleveland Browns | Hanford Dixon | DB | Southern Mississippi |
| 1980 | Tampa Bay Buccaneers | Ray Snell | G | Wisconsin |
| 1979 | Denver Broncos | Kelvin Clark | T | Nebraska |
| 1978 | Pittsburgh Steelers | Ron Johnson | DB | Eastern Michigan |
| 1977 | Cincinnati Bengals | Mike Cobb | TE | Michigan State |
| 1976 | St. Louis Cardinals | Mike Dawson | DT | Arizona |
| 1975 | San Diego Chargers | Mike Williams | DB | Louisiana State |
| 1974 | Dallas Cowboys | Charley Young | RB | North Carolina State |
| 1973 | Cleveland Browns | Pete Adams | G | USC |
| 1972 | Baltimore Colts | Tom Drougas | T | Oregon |
| 1971 | Baltimore Colts | Don McCauley | RB | North Carolina |
| 1970 | Los Angeles Rams | Jack Reynolds | LB | Tennessee |
| 1969 | Oakland Raiders | Art Thoms | DT | Syracuse |
| 1968 | Kansas City Chiefs | George Daney | G | Texas-El Paso |
| 1967 | Buffalo Bills | John Pitts | DB |
Arizona State |
